The disruptions were also sex-specific — affecting donor liver cells of males and females in different ways, according to the research.
“These chemicals change our bodies,” said senior author Ana Maretti-Mira, an assistant professor of research medicine at the University of Southern California’s Keck School of Medicine, in a statement.
Several of these compounds, also known as perfluoroalkyl and polyfluoroalkyl substances (PFAS), interrupt liver cell signaling and immune functions but do so via unique mechanisms, scientists observed in the study, published in Environment International.
The disruptions were also sex-specific — affecting donor liver cells of males and females in different ways, according to the research.
“These chemicals change our bodies,” said senior author Ana Maretti-Mira, an assistant professor of research medicine at the University of Southern California’s Keck School of Medicine, in a statement.



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