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Monday, Oct 13th

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How to prevent CTE on and off the football field

How to prevent CTELate last month, the New York City medical examiner confirmed the man who shot and killed four people at a Manhattan office tower had the degenerative brain disease Chronic Traumatic Encephalopathy, also known as CTE.

The shooter, Shane Tamura, targeted the NFL headquarters in July. He left a note at the scene, claiming to suffer from CTE. He blamed football, which he played from age 6 through high school.

Tamura shot himself in the chest. His letter urged scientists to study his brain. That note included the names of prominent researchers in the field, including neuroscientist Chris Nowinski, CEO of the Concussion Legacy Foundation and a former professional wrestler.

Nowinski said he wasn’t surprised by Tamura’s diagnosis.

“CTE risk in football players, we know from the work at the Boston University CTE Center, is related to how many years of football you play. And we don't know where it starts, but the research thus far suggests it goes up by as much as 30% per year you play, your odds increase,” Nowinski said. “And in our experience now at BU studying hundreds of football players, if you get to 12 seasons, more than half of those that we've studied have had it.”

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Federal judge blocks Trump changes to teen pregnancy prevention program

Planned ParenthoodThe Trump administration can’t force organizations that receive federal teen pregnancy prevention grants to comply with an executive order against “indoctrinating” children about “radical gender ideology,” a federal judge ruled Tuesday. 

U.S. District Judge Beryl Howell in Washington, D.C., an appointee of former President Obama, ruled that a July directive from the Department of Health and Human Services (HHS) was arbitrary and capricious and contradicted the original congressional intent of the grants.

Howell said HHS imposed binding requirements on grant recipients but gave no indication that those requirements “were the product of reasoned decision-making and analysis of evidence.”

Instead, the agency “seemingly relied on irrelevant ideological factors, and did not justify its change in position,” Howell wrote.

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Animal welfare is now part of RFK Jr.’s MAHA agenda

Animal welfare part of MAHARobert F. Kennedy Jr.’s making animal welfare a component of his Make America Healthy Again mission.

The health secretary has asked his agencies to refine high-tech methods of testing chemicals and drugs that don’t involve killing animals. He thinks phasing out animal testing and using the new methods will help figure out what’s causing chronic disease. It’s also got an ancillary benefit for Republicans: Animal-rights advocates like what they’re hearing.

That’s another opportunity for President Donald Trump to co-opt a traditionally left-leaning constituency.

“No one likes to see suffering,” Emily Trunnell, director of science advancement and outreach at People for the Ethical Treatment of Animals, told POLITICO. “The animal welfare benefits are very obvious to most people.”

Last week, the National Institutes of Health announced it would spend $87 million on a new center researching alternatives to animal testing and permit agency-supported researchers to use grant funding to find homes for retired lab animals.

Kennedy signed off because he thinks the new methods will enable scientists to more quickly and inexpensively draw conclusions about how chemicals and drugs work. He expects that’ll confirm his belief that chemicals in the environment and in food are making Americans sick and also speed cures for chronic diseases like cancer, heart disease and diabetes.

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Nobel Prize in medicine awarded to trio of scientists for immune discoveries

Nobel Prize in Medicine

scientists Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi from Japan won the 2025 Nobel Prize in Physiology or Medicine on Monday for their discoveries in controlling the immune system, creating openings for possible new autoimmune disease and cancer treatments.

This year's prize "relates to how we keep our immune system under control so we can fight all imaginable microbes and still avoid autoimmune disease," said Marie Wahren-Herlenius, a rheumatology professor at the Karolinska Institute.

Sakaguchi told reporters outside his university laboratory that "I feel it is a tremendous honour," Kyodo news agency reported.

The winners for medicine are selected by the Nobel Assembly of Sweden's Karolinska Institute medical university and receive a prize sum of 11 million Swedish crowns ($1.2 million), as well as a gold medal presented by Sweden's king.

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FDA Approves A New Generic Version Of The Abortion Pill

FDA okays generic for birth controlThe Food and Drug Administration has approved a new generic version of the abortion pill mifepristone, prompting an outcry from conservatives who’ve been eager to restrict access to the medication.

The generic pill was approved in September, according to Evita Solutions, its manufacturer. It joins another generic pill that’s already on the market from GenBioPro, which was approved in 2019.

Andrew Dixon, a spokesperson for the Health and Human Services Department, noted that the FDA “has very limited discretion in deciding whether to approve a generic dMore...rug. By law, the Secretary of Health and Human Services must approve an application if it demonstrates that the generic drug is idMore...entical to the brand-name drug.”

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Study details how ‘forever chemicals’ disrupt liver function

Forever chemicalsThe disruptions were also sex-specific — affecting donor liver cells of males and females in different ways, according to the research.

“These chemicals change our bodies,” said senior author Ana Maretti-Mira, an assistant professor of research medicine at the University of Southern California’s Keck School of Medicine, in a statement.

Several of these compounds, also known as perfluoroalkyl and polyfluoroalkyl substances (PFAS), interrupt liver cell signaling and immune functions but do so via unique mechanisms, scientists observed in the study, published in Environment International.

The disruptions were also sex-specific — affecting donor liver cells of males and females in different ways, according to the research.

“These chemicals change our bodies,” said senior author Ana Maretti-Mira, an assistant professor of research medicine at the University of Southern California’s Keck School of Medicine, in a statement.

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UMich and Gaza-affiliated researchers find drug-resistant bacteria amid Gaza’s collapsing health care system

Drug  resistant bacteria found in GazaThroughout the last two years, Gaza has faced widespread destruction as a result of Israel’s ongoing military campaign in the region, including the collapse of its health care system. Al-Ahli Arab Hospital is the last-standing partly-functional hospital in Gaza City. According to a study published in The Lancet Infectious Diseases, infections are spreading rapidly at the hospital due to inadequate resources to provide comprehensive health care.

In an interview with The Michigan Daily, Bilal Irfan, co-author of the study and a researcher at the University of Michigan, said the study analyzed hospital specimens over 10 months, most of which were from trauma wound materials.

“A major takeaway is that two-thirds of the study sample found there to be multidrug-resistant bacteria in the Al-Ahli Arab Hospital in Gaza City,” Irfan said. “Another major finding is that about 76% of that sample did come from blast- or trauma-related injuries, which speaks to the volume of blast-related injuries that are coming in as a result of the Israeli military assault on Gaza.”

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