
The Hamas-run civil defence agency said Israeli troops fired on crowds near the aid site in Khan Younis. More than 200 people were reportedly injured.
The Israeli military has told the BBC it is looking into the reports.
It is the latest, and potentially the deadliest, of the almost daily shootings that have been taking place recently near aid distribution sites in Gaza.
Almost all the casualties in Gaza in recent days have been linked to the delivery of aid rather than Israeli strikes on Hamas targets.