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Tuesday, May 13th

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FDA seeks less acetaminophen in prescription drugs

VicodenU.S. health regulators are requesting a limit on the amount of acetaminophen in prescription pain medicines in an effort to curb the risk of liver damage.

The move announced on on Thursday aims to limit combination drugs such as the opioids Percocet and Vicodin to 325 milligrams of acetaminophen per pill and calls for them to carry a "black box" warning about potential liver failure.

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2010's Hall of Shame -The Year in Pills

pills2010 will go down as the year the diet pill Meridia and pain pill Darvon were withdrawn from the market and the heart-attack associated diabetes drug Avandia was severely restricted.

But it was also the year the Justice Department filed the first criminal, not civil, charges against a drug company executive. Lauren Stevens, a former VP and assistant general counsel at GlaxoSmithKline, hid some 1,000 instances of GSK-paid doctors illegally promoting Wellbutrin to other doctors, say authorities.

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Autism Advocacy Organizations and Parent Groups Support Dr. Andrew Wakefield

...Urging Both Scientists and Journalists to Do More Thorough Research Into Vaccines and Autism.

Last week, an article in the British Medical Journal (BMJ), written by a freelance newspaper reporter, Brian Deer, created a media firestorm in the United States. In his article, Brian Deer accuses Dr. Andrew Wakefield of deliberate fraud regarding his 1998 case series, which was published in the British journal, The Lancet.  Dr. Wakefield reported that the children in his case series were suffering from a novel form of bowel disease and that parents reported a temporal link between the onset of symptoms and receipt of the MMR vaccine. Contrary to what has been reported in the media over the years, Dr. Wakefield never stated that the MMR vaccine caused autism. The full text of the original paper is available at www.generationrescue.org.

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Nearly 50 Percent Of Mental Health Services Recipients In Giffords' County Were Dropped In 2010

50 Percent Of Mental Health Services Recipients In Giffords' County Were Dropped In 2010In the past year, Pima County, Ariz., where Democratic Rep. Gabrielle Giffords and 19 others were shot Saturday, has seen more than 45 percent of its mental health services recipients forced off the public rolls, a service advocate told The Huffington Post.

The deep cuts in treatment were protested strongly at the time, with opponents warning that they would result in a spike in suicide attempts, public disturbances, hospitalizations and brushes with the police.

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Analysis shows heart, stroke risk of pain drugs

Analysis shows heart, stroke risk of pain drugsCommon painkillers such as ibuprofen and diclofenac as well as branded pain drugs from Pfizer Inc, Merck & Co Inc and Novartis AG can increase the risk of heart attacks and strokes, a review found on Wednesday.

Scientists from Bern University in Switzerland analyzed data from 31 trials involving more than 116,000 patients taking either naproxen, ibuprofen, diclofenac, Pfizer's Celebrex, or celecoxib, Merck's Arcoxia, or etoricoxib, Merck's Vioxx, or rofecoxib, Novartis' Prexige, or lumiracoxib, or a placebo, to try to give an estimate of the heart risks of such medicines.

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Lies, Damned Lies, and Medical Science

Dr. John IoannidisMuch of what medical researchers conclude in their studies is misleading, exaggerated, or flat-out wrong. So why are doctors—to a striking extent—still drawing upon misinformation in their everyday practice? Dr. John Ioannidis has spent his career challenging his peers by exposing their bad science.

But beyond the headlines, Ioannidis was shocked at the range and reach of the reversals he was seeing in everyday medical research. “Randomized controlled trials,” which compare how one group responds to a treatment against how an identical group fares without the treatment, had long been considered nearly unshakable evidence, but they, too, ended up being wrong some of the time. “I realized even our gold-standard research had a lot of problems,” he says. Baffled, he started looking for the specific ways in which studies were going wrong. And before long he discovered that the range of errors being committed was astonishing: from what questions researchers posed, to how they set up the studies, to which patients they recruited for the studies, to which measurements they took, to how they analyzed the data, to how they presented their results, to how particular studies came to be published in medical journals.

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A fat tummy shrivels your brain

HAVING a larger waistline may shrink your brain.

Obesity is linked to an increased risk of type 2 diabetes, which is known to be associated with cognitive impairment. So Antonio Convit at the New York University School of Medicine wanted to see what impact obesity had on the physical structure of the brain. He used magnetic resonance imaging to compare the brains of 44 obese individuals with those of 19 lean people of similar age and background.

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